Researchers have discovered a single gene mutation that may cause both diabetes and insulinomas.
Diabetes is a condition in which the body is unable to produce enough of the hormone insulin, or it cannot use it effectively.
As a result, blood sugar levels become too high.
It is estimated that around 30.3 million people in the United States are living with diabetes. Type 2 diabetes is the most common form, followed by type 1 diabetes.
But there are some rarer forms that account for just 1–4 percent of cases in the U.S. These are known as monogenic diabetes, and they arise from a mutation in a single gene that is passed down from one or both parents.
Such mutations impair the function of beta cells, which are cells in the pancreas that secrete insulin.
One of the commonest forms of monogenic diabetes is maturity onset diabetes of the young, which accounts for approximately 2 percent of all diabetes cases in the U.S. among people under the age of 20.
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